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20/12/2020

Corona vaccine, its effectiveness and its level of safety


The coronavirus vaccine has become the talk of the day in every country around the world, as public health officials hope that at least 75% of the world's population will receive one of the vaccines that have been issued so that collective immunity is achieved and the Covid 19 epidemic is stopped. Thus, people return to their normal lives and enjoy their lives, their anniversaries and events.

Corona vaccine, its effectiveness and its level of safety


Regarding the vaccine, its effectiveness, and its level of safety, the newspaper  Washington Post  published the answers of the experts in this regard, and it came as follows:


How does the Pfizer-Bionic vaccine work and what dose is needed?


"The first approved vaccine was developed in the United States by the American pharmaceutical company Pfizer and the German Biotech". Two doses are given three weeks apart. "The Pfizer vaccine is the first vaccine to use messenger RNA technology, approved for human use by the United States Food and Drug Administration".


The Pfizer vaccine also differs from more traditional vaccines, which often use a weak or dead version of the virus, or a lab-generated protein, because the new vaccine uses complex fragments of genetic information inside a protective lipid layer, to keep it from disintegrating, and when it moves to the muscle cells of the upper arm, it contains molecular instructions that tell cells in the human body to start producing a protein that leads to an immune response to the protein on the surface of the Coronavirus. 

This means that the immune system will be ready to eliminate the pathogen if it tries to invade the person who is subsequently exposed to infection.


How safe is the new vaccine?


"The FDA approved the vaccine for people 16 years of age and older after reviewing data from 44,000 participants in a randomized clinical trial". And a 53-page FDA analysis found that some people who received the injections had bothersome but tolerable side effects, including fatigue, headaches, muscle pain, joint pain, chills, and fever. 


Experts also said that a two-month follow-up process on 38,000 of these participants proves that there is "adequate security, with no specific security concerns that would prevent the issuance of an emergency use permit".



Does the vaccine protects against the coronavirus?


Two-dose Pfizer-Bionic vaccine is 95% effective in randomized trials


The results of the FDA's independent review showed that of more than 20,000 people who received two doses of the vaccine, only eight were infected with the Coronavirus and only one became seriously ill. In contrast, 162 people in the placebo group contracted the coronavirus and nine of them became seriously ill.


There is even evidence that the first dose of the vaccine protects against disease, but the FDA said: "there was not enough data to draw firm conclusions." It is also not known whether the vaccine prevents both infection and disease, raising a question that has major implications for the spread of the virus.



What are the contraindications to vaccination?


The US journal also published answers on who should get the vaccine and what are the contraindications for receiving doses of the vaccine, as follows:


Should people who have already contracted COVID-19 be vaccinated?


The American Center for Disease Control and Prevention ( CDC ) says that all members of authorized groups should receive the vaccine, whether or not they have a previous infection.


Research is still being done to establish how long immunity to the Coronavirus persists after infection or vaccination According to what experts in the epidemiology field confirm, this infection generally results in better immunity than the virus. vaccine, but vaccines such as Tetanus or HPV vaccine offer better protection than cure from regular infections.


Can a person who already has Covid-19 receive a dose of the vaccine?


It is better to wait until the end of the vaccination after the illness has recovered. All self-isolation criteria and procedures must be met to avoid infecting others. The recommended minimum vaccination period after recovery has not yet been established.


How safe is it for a pregnant woman, who is planning a pregnancy soon or who is breastfeeding?


Medical services experts advise pregnantly or breastfeeding women who wish to be vaccinated to consult a doctor first, as pregnant women have been excluded from coronavirus vaccine trials, so there are no data on the vaccine safety for them.



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